Researchers have identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA. The finding ...

DNA topoisomerase 1 is an enzyme present in all organisms, essential for cell proliferation. Its function is based on two catalytic steps: firstly, it cuts and then relinks the DNA, thus relaxing ...

DNA topoisomerase 1 is an enzyme present in all organisms, essential for cell proliferation. Its function is based on two catalytic steps: firstly, it cuts and then relinks the DNA, thus relaxing ...

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid ...

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies.

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies. As a SUMO ...

The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting is scheduled to take place in Chicago, Illinois, USA from May 30 to June 3. Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (6990 ...

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (the "Company") announced that a new indication application (the "Application") for the Company's trophoblast cell-surface antigen 2 (TROP2)-directed ...