BMS-986458 features three stereocenters, one of which epimerizes easily, Mortensen said. The drug candidate, which would be ...

Purpose: The basic concepts of pharmacogenetics, pharmacogenetic study approaches, factors to consider when applying pharmacogenetic discoveries to patient care, and potential roles for ...

To tell if prepared and processed foods or beverages contain phosphorus, look for ingredients with the word “phosphate” in them. Processed foods and beverages often contain phosphate additives ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. An evolutionarily conserved micropeptide, ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. The PCR-amplified complementary DNA fragments were assembled ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The globo-series glycosphingolipids (GSLs) are unique glycolipids exclusively ...

The major use for phosphorus is as an essential nutrient for all plant and animal life, commonly as phosphate in inorganic fertiliser. At the same time, phosphates and organophosphates are widely used ...

It also is one of the essential components in producing uridine diphosphate n-acetylglucosamine (UDP-GlcNAc), which is a very important element for maintaining the expression of transcription factor c ...

And numerous genes involved in de novo nucleotide synthesis, pentose phosphate pathway (PPP) and dNTP production were significantly inhibited, which may be associated with decreased BMDMs ...

Real-time qPCR was performed using SYBR Premix ExTaq II in a CFX96 Real-Time qPCR Detection System (Bio-Rad). Glyceraldehyde 3-phosphate dehydrogenase (Gapdh) was used as internal control. The ...