Many transcription factors in human cells have ... its ability to activate a subset of its target genes. The p53 yeast assay is now used to detect mutations in tumours 64, and at least one ...

Transcription is the process by which an RNA ... MPRAs and in vivo transgenic mouse assays are two potentially complementary ways to assay the impact of noncoding variants. Here, authors find ...

A study introduces a CRISPR model that predicts gRNA activity more accurately using chemically synthesized gRNAs. The model ...

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...

The South African Health Products Regulatory Authority (SAHPRA) has announced the approval of the first WHO Emergency Use Listing (EUL) for a test kit for mpox.

South Africa has approved the first mpox diagnostic test, bolstering efforts to improve testing access across the globe.

Unraveling the Complexities, Risks, and Latest Breakthroughs in Diagnosis and Treatment Introduction to Coxsackievirus: Classification and Virology Epidemiology and Global Distribution Patterns ...

Osteogenic differentiation is essential for bone development, metabolism, and repair; however, the underlying regulatory relationships among genes remain poorly understood. To elucidate the ...

The approved diagnostic, the Alinity m MPX assay, was developed by Abbott Molecular and is licensed to Abbott Laboratories ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...