Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity ...

A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have ...

The research team demonstrated that innate immune cells called Natural Killer (NK) cells that express CD8a on the cell surface (a receptor usually associated with T cells) are reactive to human ...

Figure 2: Binding of B7-H1 to CTLA4, ICOS and CD28. We measured the amounts of IL-2, IL-4, IFN-γ and IL-10 produced by T cells after stimulation with B7-H1Ig, B7-1 immunoglobulin (B7-1Ig ...