However, far less is known about how stem cells and their progeny maintain normal adult tissue homeostasis in vivo. Recently, we reported studies of cell fate in murine tail epidermis that ...

The hair follicle is a major repository for epidermal stem cells. Learning more about the processes that regulate the differentiation of these cells will improve the prospects for skin replacement ...

"We discovered at least two different stem cell populations – one that regenerates tissues such as epidermis and neurons, and another that forms muscles and connective tissue," says Adelmann.

As a self-renewing organ maintained by multiple distinct stem cell populations, the skin epidermis represents an outstanding, clinically highly relevant research paradigm to address these questions.

“We’re learning that it is the basic mechanisms that stem cells use to make and repair tissue that ... Fuchs has been hooked on decoding and unraveling the complicated biology of epidermal cells. In ...

"We discovered at least two different stem cell populations—one that regenerates tissues such as epidermis and neurons, and another that forms muscles and connective tissue," says Adelmann.

Inflamed mouse stem cells located in the basal layer (red) of the epidermis and FOS (green), a near-universal stress response factor essential to inflammatory memory. Disclaimer: AAAS and EurekAlert!

The body calls on all the stem cells that are in the vicinity of the wound. It doesn’t matter if they’re hair follicle, epidermal, or glandular stem cells. During homeostasis, hair follicle stem cells ...