2013). In this group, there are almost no apoptotic cells located in the outer enamel epithelium, even in very late stages when the enamel organ is large and stellate reticulum is expanded (Landova ...

When FFA are overaccumulated or their disposal is not timely, the redundant FFA act as substrates to produce lipotoxic lipids, which lead to endoplasmic reticulum (ER ... in the activation of hepatic ...

Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators in liver fibrosis—have a commanding role in ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

This manuscript presents a detailed characterization of male and female wildtype and Ctrp10 knockout mice, and reveals that knockout mice develop female-specific obesity that is largely uncoupled from ...

Background—The pathogenesis of pancreatic fibrosis is unknown. In the liver, stellate cells (vitamin A storing cells) play a significant role in the development of fibrosis. Aims—To determine whether ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Coal worker’s ...

A few recent examples (of many papers) include that succinate promotes tuff cell differentiation, dipeptide aldehydes from Clostridium sporogenes that can enhance endoplasmic reticulum stress, and ...