Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

a group of membrane-bound proteins that mediate vesicle fusion in endocytic and secretory pathways, was required for the 6-OHDA-induced extracellular secretion of PARK7. The researchers also ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Researchers have identified how autophagy and chaperone-mediated autophagy (CMA) drive the unconventional secretion of PARK7, ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence ...

Millions of people around the world suffer from chronic low back pain, often finding relief only through temporary solutions ...

Objective Neonatal sepsis is a significant cause of morbidity and mortality, particularly in preterm infants. Despite its ...

Both physiological and pathophysiological responses of MCs are mediated by the release of inflammatory mediators, many of which are stored, preformed, in secretory granules (SGs), and released by ...