med.kuleuven.ac.be Introduction: Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment of irritable bowel syndrome (IBS) although evidence of their efficacy is scarce.

US researchers have identified a widely used antidepressant drug that could shrink the growth of tumour and help the immune ...

SSRIs enhance CD8 T cell antitumor activity by inhibiting SERT, an immune checkpoint in tumors, suggesting potential repurposing for cancer immunotherapy. High intratumoral SERT levels correlate with ...

“SERT made for an especially attractive target because the drugs that act on it-SSRIs-are widely used with minimal side effects.” The researchers tested SSRIs in mouse and human tumor models ...

eDepartment of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada fDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, ...

SSRIs, which include well-known medications like Prozac and Celexa, work by blocking a protein called serotonin transporter (SERT). This action increases levels of serotonin, often called the ...

Division of Pharmaceutical Sciences, Mylan School of Pharmacy, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, United States Departments of Chemistry and Biochemistry, Center ...

† Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, United States ‡ Research and Development, Eli Lilly and Company Ltd., Sunninghill Road, ...

This article originally appeared on Undark. In 2006, a new study on antidepressants was making headlines with its promising results: Two-thirds of participants who tried various antidepressants ...

LOS ANGELES — Saffron may help treat sexual dysfunction related to selective serotonin reuptake inhibitors (SSRIs), new research suggests. Results of a preliminary new review found saffron ...