Ischemia and reperfusion are relevant to many disease states ranging from the impact of diabetes on the retina to stroke, cardiovascular disease and kidney dysfunction. 1,2 However, the current ...

Activation of these receptors before ischemia or during reperfusion has been proven to grant cardioprotection; for instance, the subtype-selective A3 agonist, IB-MECA, displays cardioprotective ...

The central retinal artery is one of the main arterial supplies for the retina. It pierces the eyeball close to the optic nerve and within the dural sheath, and it branches and supplies the inner ...

The consequences of ischemic heart disease result from the subsequent effects of acute ischemic reperfusion injury (IRI), which causes the death of cardiomyocytes, cardiac failure, the development ...

Boehringer Ingelheim today presented positive data from the HORNBILL Phase I/IIa study of BI 764524, the first ever study exploring a potential treatment for people living with diabetic macular ...

Bax-induced cell death is also a major cause of various neurodegenerative conditions, including glaucoma, ischemia-reperfusion injury, amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease.

Boehringer Ingelheim today presented positive data from the HORNBILL Phase I/IIa study of BI 764524, the first ever study exploring a potential treatment for people living with diabetic macular ...