Calcium pyruvate is a popular supplement often used to promote weight loss. It may have anti-inflammatory effects that could benefit gut and bone health, though more research is needed.

Pyruvate kinase deficiency has been identified in over 500 families. However, research shows that the condition could be highly underdiagnosed, as there is no way to identify mild cases.

In this global, phase 3, randomized, placebo-controlled trial, we evaluated the efficacy and safety of mitapivat in adults with pyruvate kinase deficiency who were not receiving regular red-cell ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to ...

Pyruvate formate-lyase (PFL) from Escherichia coli uses a radical mechanism to reversibly cleave the C1-C2 bond of pyruvate using the Gly 734 radical and two cysteine residues (Cys 418, Cys 419 ...

For lactate and pyruvate analysis, arterial blood collected in a syringe was transferred within twenty seconds to weighed flasks of chilled 3.5 per cent perchloric acid.

Cheap, eco-friendly catalyst opens new possibilities for organic molecules built from pyruvate Date: March 24, 2022 Source: Okinawa Institute of Science and Technology (OIST) Graduate University ...

The NDA is supported by data from a double-blind, crossover phase 3 study evaluating SL1009 in young children with a confirmed pathological mutation in the pyruvate dehydrogenase complex.

Known as the mitochondrial pyruvate carrier, this molecular machine was first proposed to exist in 1971, but it has taken until now for scientists to visualise its structure at the atomic scale ...

Exogenous pyruvate plays a pivotal role in maintaining glycolysis–TCA cycle flux and ATP production under high-glucose conditions by suppressing PARP activity.