Protein kinase C (PKC) is as a family of serine/threonine kinases that can be activated by Ca 2+, phospholipid and diacylglycerol. PKC plays an important role in oocyte maturation and activation.

A new chemical compound has been making a big impression in the fight against cancer in recent years. Now it seems EBC-46, ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

Learn how the molecule EBC-46 could advance how HIV is treated and how researchers discovered it.

The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity that ... Activation of the phospholipase C-γ (PLCγ) pathway is also thought ...

Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

IDEAYA Biosciences, Inc. (NASDAQ:IDYA – Get Free Report) has earned an average rating of “Moderate Buy” from the sixteen analysts that are covering the firm, Marketbeat.com reports. Two research ...

ucl.ac.uk Recognising lamin A/C heart disease is important because implantable cardioverter defibrillators need to be implanted early. Promising oral drug therapies are within reach thanks to research ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

The US Food and Drug Administration has approved mirdametinib for the treatment of neurofibromatosis type 1 (NF1) in adults ...