The concept of stroke MRI mismatch based on qualitative evaluation of diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) has been applied in clinical practice for several years. The ...

Background and Purpose— For MR perfusion–diffusion (PWI-DWI) mismatch to become routine in thrombolysis patient selection, rapid and reliable assessment tools are required. We examined interrater ...

Methods— Raw perfusion images were used to generate maps of time to peak (TTP), mean transit time (MTT), time to peak of the impulse response (Tmax) and first moment transit time (FMT). DWI, apparent ...

Background and Purpose— The perfusion–diffusion mismatch (PDM) model has been proposed as a tool to select acute stroke patients who are most likely to benefit from reperfusion therapy. The ...

Background and Purpose—Perfusion imaging has the potential to select patients most likely to respond to thrombolysis. We tested the correspondence of computed tomography perfusion (CTP)-derived ...

Abstract Background and Purpose —Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) are relatively new MR techniques increasingly used in acute stroke. During the first hours of ...

We present our initial experience with a supervised technique for calculating the mismatch between lesion volumes on perfusion and diffusion weighted images of acute stroke. Our method was designed to ...

The Desmoteplase in Acute Ischemic Stroke Trial (DIAS-1) looked at patients who were 3 to 6 hours out from stroke onset and had a perfusion/diffusion mismatch on imaging of 20% or greater (Stroke ...

After having been selected by the so-called perfusion/diffusion "mismatch" present on MRI, 38 patients were randomized.

PIM – mismatch between perfusion deficit and ischemic core: Mismatch ratio >1.8, mismatch volume >15 ml, core volume <70 ml, as determined by 3 different measures to define the perfusion deficit (DT ...