Abstract: Selecting degenerate primers for multiplex polymerase chain reaction (MP-PCR) experiments, called the degenerate primer design problem (DPDP), is an important problem in computational ...

This important study provides evidence for asymptomatic Bordetella pertussis carriage among mothers in a longitudinal cohort in Zambia, significantly advancing understanding of transmission dynamics.

Primer coverage was evaluated using in silico PCR via the TestPrime 1.0 online tool ... revealing the complex interplay between the intergenomic variation and primer design in 16S rRNA gene sequencing ...

PCR primer design should avoid possible amplification of sequences from homologous genes (eg, NLRP genes). The Human Genome Variation Society (HGVS) has recommended avoiding the use of ‘mutation’ and ...

In this interview, we catch up with Jue Wang from Google DeepMind to learn more about computational protein design.

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Michael Dong recently discussed sample preparation (SP) techniques for small-molecule drug substances and solid dosage forms.