aeruginosa—one of the most prevalent infection-causing bacteria in cystic fibrosis—and evidence of phage-resistant bacteria having reduced pathogenicity in the nine adults treated with this ...

So why are certain cholera strains so successful at evading phage attacks? Could this either enable or enhance the pathogen's devastating effect on human populations? One event stands out.

The US government has provided almost $24 million in funding to Locus Biosciences to support a mid-stage trial of LBP-EC01, a CRISPR-engineered bacteriophage therapy in development for resistant ...

This defense system detects DNA from an invading phage and cuts it into pieces before the phage can take over the cell. But some phages have developed counter-defenses that inhibit this system ...

SpacePHARER is a modular toolkit for sensitive phage-host interaction identification using CRISPR spacers. SpacePHARER adapts the fast homology search capabilities of MMseqs2 to sensitively query ...

Viruses play a crucial role in microbial communities and can significantly influence ecosystem processes and biogeochemical cycles by regulating the structure of these communities and the metabolic ...

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