Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

New model for replication of BKPyV virus, a major cause of kidney transplant failure Date: December 6, 2024 Source: University of Alabama at Birmingham Summary: BK polyomavirus, or BKPyV, is a ...

News Release 6-Dec-2024 New model for replication of BKPyV virus, a major cause of kidney transplant failure There are no effective antivirals against BK polyomavirus in transplanted kidneys.

Researchers have shown unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The ...

As the team reports in its new paper, "Compound 27 is the first Mac-1-targeted small molecule demonstrated to inhibit coronavirus replication in a cell model." ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...