IT has been demonstrated that, besides heparin and histamine, mast cells contain serotonin (5-hydroxytryptamine, 5-HT) 1–3. However, serotonin-containing mast cells, having been found ...

WHILE examining the histology of tuberculoid and lepromatous skin lesions of leprosy, we noted that there were many cells containing acid-fast granules in the cytoplasm, around the granulomatous ...

When implanted in mice, the engineered fat successfully starved tumors, leading to the elimination of breast, pancreatic, and prostate cancer cells. Ahituv emphasized the advantages of using fat ...

Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial. They line blood vessels, regulating blood flow and inflammation, and their cell junctions are the ...

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel ...

We hypothesize that thalamic mast cells contribute to inflammation and pain, by releasing neuro-sensitizing molecules that include histamine, IL-1β, IL-6 and TNF, as well as calcitonin-gene related ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

The program has shown strong ... Outside-in Signaling Shows a Route Into Cancer Cells Feb. 4, 2025 — A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked ...

Scientists in China have developed a modified virus found in birds that causes cancer cells to produce sugars the immune system can easily recognize and attack. The experimental therapy was tested ...

Ubisoft is apparently endeavoring to work with Tencent to bring forth new ventures, one of which is the rumored Splinter Cell Remake. During an address, Guillemot confirmed numerous titles were in ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven ...

Because DNA damage can be fatal to cells, drugs that target PARP1 in cancer cells and arrest DNA repair by fixing the glue in its “solid” form might kill them. Organizing complex biochemical ...