In recent years, the integration of biophysical techniques with molecular simulations and artificial intelligence (AI) has revolutionized our understanding of biomolecular and cellular properties.

PSA responses were seen both in patients with androgen receptor wild type (including androgen receptor amplification) and ligand binding domain mutations, the investigators pointed out. No grade 4 ...

For more information, please visit www.veratx.com About Atacicept Atacicept is an investigational recombinant fusion protein that contains the soluble transmembrane activator and calcium-modulating ...

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...

Longer survival was seen in those with melanoma who received programmed cell death receptor-1 or its ligand who had a low neutrophil-lymphocyte ratio.

CXCR4 receptor stimulation by its ligand, CXCL12, has been shown to play a key role in the movement of white blood cells (leukocytes) to and from the bone marrow compartment. Full prescribing and ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

In line with the restructuring initiative, 23andMe is looking for strategic opportunities for its pipeline assets, including ...

Johnson & Johnson has announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorization for BALVERSA®▼ (erdafitinib) as a monotherapy for the treatment ...

Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies ...

Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...

In particular, IL-18BP serves as a “decoy receptor” that binds to IL-18 with higher affinity ... immune cell responses and increases the production of Programed Death Ligand 1 (PD-L1) on tumor cells.