We investigated lectin pathway cord blood concentrations in infants with neonatal sepsis. Study design: Case-control study including 47 infants with culture-proven neonatal sepsis and 94 matched ...

Narsoplimab, also known as OMS721, is a monoclonal antibody targeting MASP-2, a key player in the lectin pathway of the complement system. The drug has received breakthrough therapy and orphan ...

Endothelial damage, which activates the lectin pathway of complement, plays a central role in the development of TA-TMA. The condition occurs in both autologous and allogeneic transplants but is ...

Interaction of nascent secretory proteins in the ER with molecular chaperones, such as BiP or the lectin chaperones calnexin ... by a proteasome-mediated pathway. A similar dependence on ...