Background: Lactylation plays an essential role in pancreatic cancer, but the precise role of lactylated histone in the diagnosis and prognosis of pancreatic cancer remains to be further clarified.

There are about 74,000 customers still without power in Northern Ireland following the devastation caused to the electricity network by Storm Éowyn. At its peak, Storm Éowyn brought winds of ...

Scientists have identified metabolic enzymes that indirectly facilitate lactylation, as well as delactylases that remove lactyl groups, but no dedicated lactyltransferases have been discovered as yet.

In the other pathway, lactate can be converted into lactyl-CoA and is involved in the lactylation of histones and nonhistone proteins. GLUT, glucose transporter, Klalysine lactylation; MCT, ...

The tumor microenvironment (TME) is characterized by interactions among various cells, including tumor cells, immune cells, stromal cells, and blood vessels mediated by factors such as cytokines and ...