Unlock the secrets of brown fat, a unique fat that burns calories and may enhance exercise performance and longevity.

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout efficiency in mammalian zygotes.

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Retinoic acid receptor alpha (RARα) is a nuclear receptor with a central role in spermatogenesis. Genetic knockout studies in mice have shown that the lack of RARα leads to a complete absence of sperm ...

Ahead of Adriano Moraes' bid for the vacant ONE flyweight MMA world championship later this week, ONE Championship took a ...

The dbl-PAC-Tg(SNCA A53T) +/+;Snca-/-model, referred to here as double-transgenic mice, are mice lacking endogenous α-synuclein (Snca knockout mice) that were crossed with two homozygous transgenic ...

A research team led by Prof. Sun Cheng from the University of Science and Technology of China (USTC), in collaboration with ...

We all watch movies like Jurassic Park and Jurassic World and marvel at the possibilities of bringing back animals and ...

Colossal Biosciences has announced the birth of the world’s first “woolly mouse”. The mouse has been genetically engineered ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...