The Krebs cycle byproduct itaconate has recently emerged as an important metabolite regulating macrophage immune functions, but its role in tumor cells remains unknown. Here, we show that increased ...

Results: We showed that the anti-inflammatory properties of GCs involve a reprogramming of the mitochondrial metabolism of macrophages, which results in an increased and sustained production of the ...

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Tetrapod endogenous retroelements (ERE) encode proteins that have been exapted to perform many roles in development and also in innate immunity, including GAG (group specific antigen) proteins from ...

m 6 A RNA methylation controls salivary gland epithelial cell function and has a protective role in Sjögren’s disease ...