Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

InhaleRx Limited engages in the developing and commercializing of medical drug delivery systems in Australia. It also develops inhaled drug formulations. The company was formerly known as Lifespot ...

The company, which secured $200 million from investors in a private funding deal last week, learned Tuesday of a serious side effect experienced by one participant on a high dose of its Rett therapy.

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from ...

Not all stressors have the same impact on health. Stress arising from threats to social safety is most likely to affect psychological, biological, and clinical outcomes. This is the conclusion ...

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The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

IRX-101 is under clinical development by IRenix Medical and currently in Phase III for Eye Infections. According to GlobalData, Phase III drugs for Eye Infections have a 43% phase transition success ...

InhaleRx Ltd focuses on medical inhalation devices for the delivery of prescribed medicines. The Medihale Inhaler utilizes heat (not burn) technology, avoiding the production of pyrolytic toxins and ...

Initial experiments used large-scale genetic techniques to measure gene activity and chromatin accessibility simultaneously in progenitor cells extracted from the lungs of mice. Khattar, Fernandes et ...

found an association between FTO rs16953002 and rs12596638 and melanoma susceptibility. However, these two SNPs are located in intron 8 of the FTO gene rather than intron 1 (the BMI-related region).

Here, we analyzed the stem transcriptome of a set of cell wall biosynthetic mutants in order to investigate whether cell wall damage, in this case caused by aberrant xylan synthesis, activates a ...