The actin-rich protrusions are the invadopodia. Transcriptome profiles of the cells with invadopodia showed that genes responsive to reactive oxygen species were upregulated in young mutant fish.

This image shows invadopodia in action. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of ...

One of the earliest events in the transition to a metastatic cancer cell is the development of finger-like projections called invadopodia that extend from the surface of the tumor cell.