The actin-rich protrusions are the invadopodia. Transcriptome profiles of the cells with invadopodia showed that genes responsive to reactive oxygen species were upregulated in young mutant fish.

This video shows invadopodia in action. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of ...

One of the earliest events in the transition to a metastatic cancer cell is the development of finger-like projections called invadopodia that extend from the surface of the tumor cell.

Cell migration is the process by which cells move from one location to another by adopting different motility modes, such as mesenchymal, amoeboid or collective migration. Cell motility is ...

Cancer Res. 2017 Jul 15;77(14):3791-3801. doi: 10.1158/0008-5472.CAN-16-2545. Epub 2017 May 22. The CD44s splice isoform is a central mediator for invadopodia activity. Zhao Pu, Xu Yilin, Wei Yong, ...