An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

Because sex and pregnancy hormones regulate RANK–RANKL signalling, we assessed the structure of intestinal villi — tiny, finger-like protrusions in the gut lining that provide a large surface ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

During fetal development, the small intestine undergoes several invaginations, where the small bowel becomes ensheathed. The result is formation of multiple villi and microvilli. Intestinal villi ...

Their work showed that the small intestine holds two types of TRM cells. These cells are split between the tiny, finger-like “villi” structures that line the small intestine or the “crypts” between ...

Intestinal villi (singular: villus)are tiny, finger-like projections that line the interior (lumen) of the small intestine. The primary function of villi is to absorb nutrients from food and transfer ...

The study shows that tissue-resident memory CD8 T cells in the small intestine are diverse with ... The frontline: At the villus tips, a subset of tissue-resident memory CD8 T cells with a higher ...