Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases.

In summary, we demonstrate the development of a novel alveolar organoid model and use it to identify effectors of SFTPC maturation necessary for AT2 health. Disorders of surfactant protein biology ...

Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating orbital mechanical stimulation to better replicate intestinal conditions and investigate nanoparticle interactions.

Researchers from the Organoid group developed a new way to grow organoids ... a specific type of extracellular matrix, to culture organoïds. Although these extracts, like Matrigel and BME, are ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth ... of ISCs and Paneth cells in terms of ex vivo ...

For example, intestinal stem cells (ISCs ... They then used a technique known as immunohistochemistry as well as an organoid forming assay to study the behavior of the cells in the intestine of mice.

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Intestinal cells, for example ... Invasin protein from Yersinia bacteria can be used as key component for organoid culture. Credit: Sensu. Hubrecht Institute. The possibility of culturing ...