Data are accumulating that emphasize the important role of the intestinal barrier and intestinal permeability for health and disease. However, these terms are poorly defined, their assessment is a ...
A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an ...
Normally, this mucus is impermeable to bacteria and thus maintains a healthy distance from the intestinal bacteria. In the ...
The disruption of the intestinal barrier allows bacteria to translocate through the bloodstream to the bone marrow, inducing epigenetic changes in immune stem cells. This trained immunity enhances ...
Discover the hidden inflammation in psoriasis patients' intestines, its link to leaky gut, and the increased risk of Crohn's disease.
Because IL-22 promotes intestinal integrity, the team next determined if these commensal Clostridia molecules reduced gut barrier permeability. They disrupted the intestinal microbiome with neonatal ...