In continuation of our studies on this species the present communication report the isolation and identification of the biosynthetically interesting indole alkaloids ... 1.0 mM sodium pyruvate, 10% ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to ...

Known as the mitochondrial pyruvate carrier, this molecular machine was first proposed to exist in 1971, but it has taken until now for scientists to visualise its structure at the atomic scale ...

Scientists have worked out the structure of this machine and shown how it operates like the lock on a canal to transport pyruvate -- a molecule generated in the body from the breakdown of sugars ...

DCA is a targeted therapy that inhibits Pyruvate Dehydrogenase Kinase (PDK) to stimulate residual Pyruvate Dehydrogenase Complex (PDC) activity and increase energy (ATP) production by mitochondria.

DCA will be used with a proprietary genetic test to treat an orphan pediatric mitochondrial disease, Pyruvate Dehydrogenase Complex Deficiency (PDCD) 1. The FDA granted Priority Review for the NDA and ...

Auxin metabolism involves several key enzymatic processes. The TAA (tryptophan aminotransferase) family catalyzes the conversion of tryptophan (Trp) into indole-3-pyruvic acid (IPA), which is ...

The paper is titled "Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice." Pyruvate, a glycolytic metabolite, was found to inhibit adipogenic ...

When sugar is metabolized, it is converted to a substance known as pyruvic acid, which is then used for energy. The enzyme that makes this conversion contains lipoic acid, niacin, and thiamin.

Fan Zhang from Sichuan University, China, provided a highly efficient Pt/CdS catalyst, realizing the upcycling of polylactic acid to green hydrogen and value-added pyruvic acid through ...

Illustration by Akshita Chandra/The New York Times; Images by PhotoObjects.net, Yuji Sakai, and THEPALMER/Getty Images By Doug Sosnik Graphics by Quoctrung Bui Mr. Sosnik was a senior adviser to ...