To determine the structure of the HIV protein coat (also know as the capsid), the researchers ran simulations at the petascale level using the Blue Waters supercomputer at the University of Illinois.

Researchers studied the 3D structure of the virus and have reported their finding in the Journal Structure. HIV virus has a wide range of variability due to difference in size and shape which ...

Unfortunately, because of the virus’s metastability, or shape-shifting tendency, structures of HIV’s proteins have proven difficult to establish for use in vaccine design. The Ward and Wilson groups ...

The authors said the discovery opens the door for important follow-up research, including studies of the HIV Pol structure of the larger and more complex polyprotein Gag-Pol, also involved in ...

Knowing the structure of the molecule you’re targeting helps you find or make a drug that will fit.” Knowledge of HIV Pol’s structure sheds new light on how HIV reproduces itself.

Scientists have determined the molecular structure of HIV Pol, a protein that plays a key role in the late stages of HIV replication, or the process through which the virus propagates itself and ...

Taking a hint from the kitchen, scientists appear to have discovered a way to produce a true structure of the rare but naturally-occurring anti-HIV compound Lancilactone C from start to finish.