Nuclear organization refers to the spatial distribution of nuclear contents and components in a way that reflects or facilitates their activities. For example, chromatin or nucleoli may become ...

Single cells are typically typed by clustering into discrete locations in reduced dimensional transcriptome space. Here we introduce Stator, a data-driven method that identifies cell (sub)types and ...

Figure 1: Overview of the IDEA protocol. The protein–DNA complex, represented by the human MAX–DNA complex structure (PDB ID: 1HLO), was used for training the IDEA model. The sequences of the protein ...

Alveolar macrophage (AM) development and function depends on signature transcription factor peroxisome proliferator-activated receptor-γ (PPARγ). The regulation of PPARγ stability during AM ...