Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows ...

Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...

However, because so many mouse genes are similar to human genes, geneticists can generate knockout mice in which the mouse counterpart of a human gene of interest is deleted or disrupted.

Gene knockout approaches completely ablate gene expression at the DNA level. 3 Researchers can accomplish this by using genome editing tools, such as zinc finger nucleases (ZFN), transcription ...

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout ...

Synthego, a leading genome engineering solutions company, today announced the launch of the Gene Knockout Kit v2. This is the only product that leverages a novel bioinformatics- powered multi-guide ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota can construct gene-targeted vectors for mice to assist researchers.

to knockout and characterize all protein-coding genes in the mouse genome. Knocking out the activity of a gene provides valuable clues about what that gene normally does. However, creating and ...

Based on early Phase I/II data, investigators at Cincinnati Children's are enrolling more patients with a telomere biology ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota makes embryonic stem (ES) cell-based gene-targeted mice available to researchers.