Genome editing technique enables partial inhibition of gene function in crops
Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows ...
The Scientist7mon
What’s the Difference Between Gene Knockdown and Gene Knockout?
Gene knockout approaches completely ablate gene expression at the DNA level. 3 Researchers can accomplish this by using genome editing tools, such as zinc finger nucleases (ZFN), transcription ...
AZoLifeSciences on MSN8mon
Applications of Gene Knockout and Knock-in Models in Disease Research
Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...
The Scientist5y
Synthego Introduces the Next Generation of CRISPR Knockout Technology with the Gene Knockout Kit v2
Synthego, a leading genome engineering solutions company, today announced the launch of the Gene Knockout Kit v2. This is the only product that leverages a novel bioinformatics- powered multi-guide ...
Nature4y
Scientists Can Analyze Gene Function by Deleting Gene Sequences
However, because so many mouse genes are similar to human genes, geneticists can generate knockout mice in which the mouse counterpart of a human gene of interest is deleted or disrupted.
Nature7y
knockout mouse
To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene of interest. This may be done by deleting portions of the gene's DNA sequence to make it nonfunctional ...
Arbor Biotechnologies Announces $73.9 Million Series C Financing to Advance Novel Gene Editing Therapeutics
Series C led by ARCH Venture Partners and TCGX with significant participation from existing and new investorsFinancing extends Arbor’s cash ...
BioWorld9d
NWD1 gene knockout tied to MASH-like phenotype in mice
The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...