This review synthesizes current knowledge on the intricate metabolic interplay between folate and biopterin cofactors, emphasizing their structural ...

The importance of putative folate-biopterin metabolic interactions lies in the role they may play in the expression of several clinically relevant phenotypes. However, to date, clinical studies on ...

In the ongoing battle against antibiotic-resistant bacteria, MSU researchers have made a discovery that could reshape how we target deadly pathogens like staph infections.

Scientists reveal how loss of a single enzyme, SDR42E1, rewires vitamin D processing and cell survival, opening new doors for cancer and metabolic therapies.

Safflower is widely valued for its flavonoid glycosides, particularly for cardiovascular therapeutics and natural dyes.

Luigi Gorini, Wenche Gundersen, Induction by Arginine of Enzymes of Arginine Biosynthesis in Escherichia coli B, Proceedings of the National Academy of Sciences of the United States of America, Vol.

"Studies have shown that this enzyme can help increase gastric motility and improve the digestion of proteins." That means your digestive system may be able to break down food more efficiently ...

These results indicate that NF2 deletion modulates de novo pyrimidine metabolism by enhancing the expression of pyrimidine biosynthetic enzymes. Given the importance of pyrimidine synthesis in ...

LOS ANGELES, CA, USA I July 30, 2025 I Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company ...

Dysregulated cholesterol biosynthesis is another metabolic event frequently observed in HCCs. HMG-CoA reductase (HMGCR) is the rate limiting enzyme in cholesterol biosynthesis and the target of ...