In motile cells, sites of adhesion within filopodia and lamellipodia are relatively small and transient and are referred to as ‘focal complexes,’ whereas adhesions underlying the body of the ...

This review focuses on the focal-adhesion adaptor protein paxillin, and discusses the role that it, and its many binding partners, play in transduction of adhesion and growth-factor signals at the ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

We explored three primary mechanisms: (1) collisions in blood flow disrupt leukocyte adhesion, (2) specific binding to the endothelium competes with leukocytes for binding sites, and (3) particle ...