Objective: To characterize the pharmacokinetic-pharmacodynamic correlation of intranasal and intravenous fentanyl in opioid-naïve patients undergoing third molar extraction. Methods: A double ...

The clearance return of 1.48 L/min was comparable to values obtained by fitting the intravenous and intranasal data separately. The bioavailability of fentanyl via the intranasal route was 89% ...

Chelsea Adolphus, a patient at an Illinois medical center, was pronounced dead 14 hours after being found unresponsive on the ...

In a city that arguably invented the notion of “good vibes” in the counterculture 1960s, newly minted San Francisco Mayor ...

The drug epidemic and addiction crisis have quickly become a defining issue of Canada’s relationship with the United States.

The White House is set totemporarily pause federal grants and loans as the Trump administration begins reviewing agency ...

A new study published in Addiction has found that opioid smoking appears to be associated with lower mortality risk compared ...

President Donald Trump signed a flurry of executive orders focused on the military, including one that directs Defense ...

• Establish the Department of Government Efficiency under the Executive Office of the President until July 4, 2026. This is ...

President Donald Trump began his second administration with a blitz of policy actions to reorient U.S. government priorities ...