Experts explain what we know about the connection between gallstones and MASLD, and what you can do to reduce the risk of ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...

Yellow or greenish vomit is a sign you're throwing up bile, a digestive fluid produced by the liver. This could indicate a serious medical concern, like a hiatal hernia or intestinal blockage. It can ...

Modern structural analyses have revealed that these modifications significantly influence receptor binding affinity and specificity, particularly for key receptors such as FXR and TGR5 (2, 3). The ...

If you buy something, we may earn an affiliate commission. What is kojic acid, exactly? To get technical, this active is a natural byproduct of fermenting fungi like Aspergillus oryzae ...

Caecal microbiota composition (Illumina Sequencing of the 16S rRNA gene) and key pathways/mediators involved in the control of vascular function, including bile acid (BA) profiling, gut and liver key ...

It has been shown that primary bile acids are capable of inducing cathelicidin gene expression in biliary epithelial cells through the FXR. Secondary bile acids that are byproducts of metabolism ...