Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Researchers have identified in a new study that oral infigratinib, an FGFR1-3 selective tyrosine kinase inhibitor, improves ...

Alternatively, it could be an early evolutionary stage for the spongy tissue (endochondral bone) filling the inside of most bones in modern land vertebrates, including humans.

Cleidocranial dysplasia (CCD) (MIM 119600) is an autosomal dominant skeletal dysplasia characterised by abnormal clavicles, patent sutures and fontanelles, supernumerary teeth, short stature, and a ...

Achondroplasia is a genetic condition resulting from specific disruptions in the formation of endochondral bone. Telecanthus, exotropia, angle anomalies and cone–rod dystrophy have been observed as ...

There is increasing evidence that T lymphocytes play a key role in controlling endogenous regeneration. Regeneration appears to be impaired in case of local accumulation of CD8+ effector T cells (T ...

5 Department of Cell Biology, New York University School of Medicine, New York, New York, USA Correspondence to Professor Xiu-Ping Yu, Institute of Pathogenic Biology, Shandong University School of ...

Regardless of age, we should all be considering ways to improve or maintain bone health. This is particularly true for people over 60, who have a higher chance of being diagnosed with osteoporosis.

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