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Probably the most iconic FPS weapon of all time would be the BFG 9000 from Doom. It's famous for its destructive power, but ...

Weapons like the Super Shotgun could be added to 76 without seeming too out of place, and there is even an argument to be made that DOOM's iconic BFG-9000 is a good match for Fallout's sci-fi ...

Also part of the Doom Anthology SteelBook is an awesome replica of the Doom series' BFG. The gun made a cameo in Quake II with the shooter's manual stating BFG stands for "Big, Uh, Freakin' Gun".