Dendritic cells are poised to revolutionize oncology. This type of immune therapy shows effectiveness even in late-stage ...

Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA ... the chromatin ...

Researchers at UC San Diego have examined the critical role of goblet cells in gut immunity and health. GCs create a mucus ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

Preclinical proof-of-concept data supports the potential of CD3 Switch-DARPin platform to activate and boost T cells in the presence of tumor ...

In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. 3School of Life Science and Technology, ShanghaiTech University, Shanghai, ...

The pre-clinical findings, published in Nature, highlight the potential to activate these cells to fight tumors more effectively, offering new hope for broader treatment success, particularly in ...

Mast Cell Activation Syndrome (MCAS) is a complex and largely misunderstood condition affecting many people worldwide. This article will explore what MCAS is, its symptoms, causes, and treatment ...

These cells, located in parts of the gut like the ileum, can activate CD8 + T cells, which are key players in the immune system and destroy harmful bacteria, viruses, and even some cancer cells.

The dendrites, when extended out, help dendritic cells sample the gut for foreign substances. When they find something dangerous, they activate immune cells like T cells. The researchers created a ...