The 2025 Golden Globes marks Moore’s first Golden Globes nod since 1997 for the thriller drama, “If These Walls Could Talk.” This time, she was nominated for Best Performance by a Female Actor in a Motion Picture – Musical or Comedy for the horror sci-fi film “The Substance.”

The roar that shook the Golden Globes when Demi Moore took the stage could probably be heard across state lines. No one, including Moore, seemed to have the 62-year-old pegged to win best performance by a female actress in a motion picture — musical or comedy,

The Golden Globes, which host Nikki Glaser introduced as “Ozempic's biggest night,” dished out awards Sunday for Demi Moore in the body horror film “The Substance,