A pioneering partnership between researchers from The Grainger College of Engineering at the University of Illinois ...

In today’s rapidly evolving scientific landscape, eliminating barriers to progress is more critical than ever. Precision medicine and targeted therapies hold great promise but are dependent on ...

DNA synthesis is the biological process by which a deoxyribonucleic acid (DNA) molecule is created. In the cell, each of the two strands of the DNA molecule acts as a template for the synthesis of ...

Figure 1: Sensitivity of fibroblast cell lines to MMS. Figure 2: DNA synthesis activity of β-pol is not required to reverse the MMS hypersensitivity of β-pol null cells. Figure 3: RP lyase ...

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

Bankrupt genetic-testing firm 23andMe agreed to sell its data bank, which once contained DNA samples from about 15 million people, to the drug developer Regeneron Pharmaceuticals for $256 million.

A new review sheds light on the complex molecular mechanisms behind Angelman syndrome (AS), a rare neurogenetic disorder, and ...

Through the deal, Tarrytown, New York-based Regeneron aims to bolster its capabilities in genomics-driven drug discovery by integrating 23andMe's trove of more than 15 million customer DNA ...

Find more information on the Altmetric Attention Score and how the score is calculated. DNA topoisomerase I (Top1) is often exploited as an imperative anticancer chemotherapeutic target due to its ...

The mechanism research revealed that TSC24 was not only an iron chelator but also a topoisomerase IIα catalytic inhibitor. Its inhibition on topoisomerase IIα was due to direct interaction with the ...