Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Imagine looking at thousands of scattered puzzle pieces and trying to guess what picture they create. Without any reference point, it's nearly impossible.

The Data Security Program (DSP), implemented by the Department of Justice's National Security Division (DOJ/NSD) under Executive Order ...

More than a billion people around the world suffer from mental disorders such as Alzheimer’s, Parkinson’s, ALS, Huntington’s, ...

FORE Biotherapeutics, a registration stage biotherapeutics company dedicated to developing targeted therapies to treat patients with cancer, today announced a $38 million Series D-2 financing. For ...

Shares of 10x Genomics and Illumina are down some 40% this year. Sales of their research equipment have been hurt by ...

Venom is a proven source of therapeutic drugs. Now, Los Alamos scientists are using AI to speed up the search for cures.

The treatment of leukemia among children could be made more precise with fewer side effects with the help of more accurate ...

Researchers have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained ...

For more than five centuries, Leonardo Da Vinci has been celebrated as a visionary artist, scientist, and inventor, known for ...

A study explains how age reshapes the blood system. In both humans and mice, a few stem cells out-compete their neighbors and gradually take over blood production. The loss of diversity results in a ...