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C&EN5d
Quantum Dots Elicit Hepatotoxicity through Lysosome-Dependent Autophagy Activation and Reactive Oxygen Species Production
We found that CdTe/CdS QDs can trigger significant apoptosis-independent nanotoxicity after their uptake by liver cells and internalization into lysosomes. Besides, the lysosomal enzymes were ...
C&EN5d
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons
Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States ...