PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Since the neuronal cytoplasm is aqueous ... creating distinct liquid phases within the cytosol. In principle, this is similar to mixing oil and water—despite both being liquids, they still ...

GTP hydrolysis is not coupled to fusion; rather, Rab conformation, which depends on the guanine nucleotide to which a Rab is bound, regulates the recruitment of docking factors from the cytosol ...

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, China Department of Gastric Surgery, Cancer Hospital of ...

Future Microbiol. 2009;4(2):223-240.

Autophagy is a highly conserved lysosomal degradation system that involves the creation of autophagosomes, which eventually fuse with lysosomes and breakdown misfolded proteins and damaged organelles ...

Diacylglycerol kinases (DGKs) are a family of enzymes that regulate the relative levels of diacylglycerol (DAG) and phosphatidic acid (PA) in cells by phosphorylating DAG to produce PA. Both DAG and ...