The antimitotic properties of parthenolide, a natural compound with known anticancer activity, have been largely ...

LM provokes substantial immune infiltration, generating a dense network of leukocytes and inflammatory cytokines within the central nervous system. Previous studies examining the immune landscape ...

Cell division is an essential biological process that removes aged cells and continuously renews tissues. In the human body, billions of cells divide each day: intestinal cells are completely renewed ...

Mitosis is the complex process in which duplicated chromosomes are condensed, segregated with the help of the mitotic spindle, and packaged in to daughter cell nuclei. Mitosis occurs in five ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase, the mitochondrial electron ...

Departments of Cell Biology [C. W. C., R. F. H., P. J. S.] and Molecular Genetics [Y. S.], University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, and ...

Peter C. Nowell; Phytohemagglutinin: An Initiator of Mitosis in Cultures of Normal Human Leukocytes *. Cancer Res 1 May 1960; 20 (4): 462–466. Possible factors responsible for the initiation of ...

This exposure to hypoxia-conditioned medium did not change Tie2 protein levels (data not shown). To investigate the effect of proinflammatory cytokines on Tie2 expression, cells were incubated in the ...

A 2021 systematic review revealed that echinacea may, in fact, decrease proinflammatory cytokines (substances secreted by immune cells) and increase anti-inflammatory cytokines. This may be especially ...