The antimitotic properties of parthenolide, a natural compound with known anticancer activity, have been largely ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

to the regulation of cytokinesis. B-cell deficiencies represent the most common type of PIDs in humans (Box 2). Starting from 4–6 months of life, in parallel with the decrease of maternally ...

and, as meiosis proceeds, is lost in a stepwise manner that correlates with the loss of sister-chromatid cohesion. Figure 1: Regulation of sister-chromatid cohesion in mitosis.

This exposure to hypoxia-conditioned medium did not change Tie2 protein levels (data not shown). To investigate the effect of proinflammatory cytokines on Tie2 expression, cells were incubated in the ...