Pancreatic cancer cells are known for being hard to treat, partly because they change the environment around them to block ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

“In this paper, we develop a 3D connective tissue model that enables us to directly quantify how exposing cells in a 3D environment to different nutrients, growth factors or drug treatments results in ...

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, ...

New model to investigate fibrosis treatments without use of animals Date: February 1, 2022 Source: Brown University Summary: A new 3D connective tissue model gives researchers a sophisticated tool ...

The findings suggest that connective tissue, and extracellular matrix proteins like lumican, operate outside of cells normally, but as disease or damage break down ECM, get sucked into and ...

From alveolar injury to extracellular matrix accumulation, the complex biology of pulmonary fibrosis is being unraveled ...

The extracellular matrix (ECM) is an ideal therapeutic substrate for functional remodelling of damaged gastrointestinal (GI) tissue, owing to its composition and roles in tissue development, wound ...

More information: Hyeonji Kim et al, Extracellular matrix-based sticky sealants for scar-free corneal tissue reconstruction, Biomaterials (2022). DOI: 10.1016/j.biomaterials.2022.121941 ...