Oral metronidazole and vancomycin have been compared to determine if one agent is more efficacious than the other. A prospective, randomized, controlled clinical trial compared metronidazole 250 ...

Clostridium difficile infection is the leading cause ... Now, an ultrasensitive C. difficile toxins A/B assay in development, is demonstrating increased sensitivity and specificity, showing ...

Learn the causes, symptoms, and treatment strategies for pseudomembranous colitis, a serious colon inflammation often triggered by antibiotics.

Clostridium difficile infection (CDI ... with positive samples then confirmed using a toxin(s) test, to distinguish toxinogenic from nontoxinogenic CDI. Although metronidazole and vancomycin ...

Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters. Infection and Immunity, 74. 11: 6339-6347.) ...

Clostridium difficile ribotype 027: relationship to age, detectability of toxins A or B in stool with rapid testing, severe infection, and mortality. Clin Infect Dis 2015;61(2):233-241.

Published today in Nature Structural & Molecular Biology, the study titled, "Structure of the full-length Clostridium difficile toxin B," sheds light on the weaknesses of TcdB, one of the toxins ...

Clostridium difficile is a health problem that affects ... difficile produces two toxins -- toxin A (TcdA) and toxin B (TcdB) -- which cause damage to intestinal cells by binding to carbohydrates ...

Recurrent Clostridium difficile infection is difficult to treat ... difficile toxin were performed in a central laboratory (Premier Toxins A&B, Meridian Bioscience) on days 14, 21, 35, and ...

difficile toxin B, which can damage the gut wall and cause inflammation, leading to diarrhoea. It is the first and only EC licensed non-antibiotic option indicated to prevent recurrence of Clostridium ...