cholesterol acyltransferase promotes the uptake of free cholesterol by HDL by a reaction called esterification. The esterification of free cholesterol into cholesterol ester produces a more ...

“CETP exchanges the cholesterol esters in the core of HDL particles” to other proteins, the NIH explains. Thus, HDL is ...

Medications alone aren't the only means to lower cholesterol levels. Some over-the-counter alternative high cholesterol treatments can help -- but others don't fulfill their promise. "While there ...

Cholesteryl esters—which consist of cholesterol molecules bonded with fatty acids—store and transport cholesterol throughout the body. As people get older, their risk of being hospitalized or ...

With this mixture phospholipids and diglycerides remain at the bottom of the plates. Cholesterol esters, triglycerides, fatty acids, free cholesterol and diglycerides migrate (cholesterol esters ...

depletion of cholesteryl esters, covalent modification of HDL apolipoproteins and attenuated antiatherogenic function of apolipoprotein AI. Low circulating levels of HDL cholesterol might ...

By binding to specific allosteric sites on LCAT, these modulators are believed to induce conformational changes that enhance the enzyme's affinity for lipoproteins, stimulate cholesterol ...

Another current area of research for LLAB involves unraveling the mechanistic principles underlying positive allosteric modulators of lecithin-cholesterol acyltransferase (LCAT). LCAT is an enzyme ...