Functional CFH is critical to prevent excessive activation of the complement system in the circulation. Using numerous unique mouse models, the researchers dissected the role of CFH in ...

The complement system’s central component – a protein named C3 – keeps the system activated by breaking into its constituent parts, C3a and C3b. The complement system is regulated by another protein ...

Complement is an amplifier of the innate immune system composed of around 30 components, and CFH functions to control complement’s activity. The hypothesis is that complement hyperactivity ...

The complement system, of which CFH is a modulator, is dysregulated in patients with these risk variants, and results in amplification of aberrant inflammatory responses in the eye.

The complement system, of which CFH is a modulator, is dysregulated in patients with these risk variants, and results in amplification of aberrant inflammatory responses in the eye.

4DMT acquires all world-wide rights to short-form human complement factor H (sCFH) from Aevitas Therapeutics, Inc.; technology invented at University of PennsylvaniaAnnounces sCFH as payload for ...

Three separate teams of scientists all pinpointed a gene called CFH for complement factor H. It is involved in a component of the immune system that regulates inflammation.